TY  - JOUR
T1  - Cervicovaginal  -HCG Test in Prediction of Spontaneous Preterm Delivery among Normal Pregnant Women
AU - , S. Abasalizadeh AU - , F. Abasalizadeh AU - , F. Sahaf 
JO  - Research Journal of Biological Sciences
VL  - 2
IS  - 6
SP  - 630
EP  - 633
PY  - 2007
DA  - 2001/08/19
SN  - 1815-8846
DO  - rjbsci.2007.630.633
UR  - https://makhillpublications.co/view-article.php?doi=rjbsci.2007.630.633
KW  - Preterm delivery
KW  -ß-HCG test
KW  -sensitivity
KW  -specificity
AB  - The chance of predicting a preterm delivery may be the keystone to preventing or at least best management of it. The aim of our study, was to test the possibility of using vaginal  -HCG level measurement to predict the spontaneous preterm delivery. In this prospective study, 150 pregnant women referred for prenatal care to Asadabadi university hospital clinic were studied. At a gestational age of 20-28 weeks, a cotton tip swab was placed into the endocervix and posterior vaginal fornix and sent to laboratory for  -HCG measurement. Data were entered into the computer and analyzed using SPSS 11 and medcalc 8 Statistical software packages. Mean age of participants was 26 years (&plusmn;25.9). Mean gestational age at time of sampling was 25 weeks. The relative risk of developing a preterm delivery for those having a vaginal  -HCG above 30 mIU mL <SUP>1</SUP> was calculated to be  2.61  (95%  CI:  1.25-5.5). The relative risk of developing a preterm delivery for vaginal  -HCG level above 45 mIU mL <SUP>1</SUP> was 4.5 (95% CI: 1.98-10.1). The test for a cutoff value of 45 was quite specific and half sensitive with a negative predictive value of 95.4%. A cervicovaginal  -HCG test with a cutt off value of 45 mIU mL <SUP>1</SUP> can predict the preterm delivery, but a combination screening of cervicovaginal  -HCG test along with clinical risk factor scoring for preterm delivery is suggested to be used in clinical practice.
ER  -