TY  - JOUR
T1  - Comparative Evaluation of the Efficacy of Praziquantel (PZQ) and Niridazole/Ambilhar (N/A) in the Treatment of Urinary Schistosomiasis among School Children Examined in Idah and Ibaji Local Government areas (LGAs) of Kogi State, Nigeria
AU - Ejima, I.A.A. 
JO  - International Journal of Molecular Medicine and Advance Sciences
VL  - 11
IS  - 1
SP  - 1
EP  - 8
PY  - 2015
DA  - 2001/08/19
SN  - 1813-176x
DO  - ijmmas.2015.1.8
UR  - https://makhillpublications.co/view-article.php?doi=ijmmas.2015.1.8
KW  - Cure rate
KW  -efficacy
KW  -niridazole/ambilhar
KW  -praziquantel
KW  -schistosomiasis
AB  - The study was carried out among school children in: Government Day Secondary School and Local Government Education Authority (LGEA) Primary School, Ejule-Ojebe in Ibaji Local Government Area (LGA) and LGEA Primary School, Idah in Idah LGA, Nigeria. It was designed to validate the already established protocol of using Praziquantel (PZQ) as a drug of choice in the treatment of schistosomiasis and other helminths. The cure rate procured by PZQ (66.7%) was significantly higher than that of Niridazole/Ambilhar (N/A) (36.0%) (p<0.05). The validation of the efficacy of praziquantel was established in this study when it was observed in one of the subjects examined whose initial egg-count at week zero was 40 eggs/10 mL urine who failed to turn up for treatment (served as a ‘control’) had egg-excretion increased significantly up to 1,420 eggs/10 mL urine in the 20th week post-treatment when re-examined. Generally, the results showed that there was significant difference (p<0.05) in the percentage cure rate in children placed on PZQ-regimen in the three schools surveyed.
ER  -