TY  - JOUR
T1  - Dynamics of Metastasis of Breast Carcinoma to Brain
AU - , Lawrence M. Agius 
JO  - International Journal of Molecular Medicine and Advance Sciences
VL  - 2
IS  - 3
SP  - 292
EP  - 298
PY  - 2006
DA  - 2001/08/19
SN  - 1813-176x
DO  - ijmmas.2006.292.298
UR  - https://makhillpublications.co/view-article.php?doi=ijmmas.2006.292.298
KW  - Dynamics
KW  -breast carcinoma
KW  -proliferation
AB  - A metastatic cascade appears to operate as a non-random predetermined system of selective advantage implicating initially a sieving effect by the first capillary beds in an organ of spread.  A seed-soil predilection appears to constitute a released system of promotion enhancing progression of tumor cell proliferation as a critical step in the metastatic cascade. One might redefine events in terms of promotion of pathways influencing subsequent acquisition of attributes.  Permeation and embolic spread via vessels would constitute a realized idealization of events primarily characterized in terms of ongoing changes in phenotype of tumor cells both as genetically unstable cells and as increasingly self-progressive pathways of strictly sequential type.
ER  -