TY  - JOUR
T1  - Proinflammatory HIV-1 Pathogenesis and Precarcinogenesis
AU - , Lawrence M. Agius 
JO  - International Journal of Molecular Medicine and Advance Sciences
VL  - 1
IS  - 2
SP  - 105
EP  - 111
PY  - 2005
DA  - 2001/08/19
SN  - 1813-176x
DO  - ijmmas.2005.105.111
UR  - https://makhillpublications.co/view-article.php?doi=ijmmas.2005.105.111
KW  - HIV-I
KW  -precarcinogenesis
KW  -systemic process
AB  - HIV-1 infection assumes the features of a systemic process affecting cellular cycling events and of inflammatory and neoplastic amplification. It would indeed appear that HIV-1 induces pathways of progression that are specifically transforming in terms of such amplification and self-amplification of cellular and microenvironmental events. The central nervous system in particular would constitute a manifestation of organ integrity that expresses the consequences of amplified transformation of pathobiologic lesions. Neoplasia of the lymphoreticular system would represent a characterization of the nature of such events as further projected by the HIV-1 infection evolving as AIDS dementia and Primary Lymphoma of the CNS and as Progressive Multifocal Leukoencephalopathy or opportunistic infection in general.
ER  -