TY  - JOUR
T1  - Experimental Mastitis in Cows Induced by Field Isolates of <i>Nocardia farcinica</i>
AU - Babiker, H. A. E. AU - Ahmed, Abdelbasit O. AU - Mahgoub, Adil AU - Hamid, Mohamed E. 
JO  - Journal of Animal and Veterinary Advances
VL  - 18
IS  - 1
SP  - 11
EP  - 17
PY  - 2019
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2019.11.17
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2019.11.17
KW  - Mastitis
KW  -cows
KW  -Nocardia farcinica
KW  -experimental infection
KW  -clinical manifestations
KW  -granulomatous
AB  - Mastitis is a common disease of lactating cows and is caused by several different types of bacteria
including <i>Nocardia farcinica</i>. The objective of the current study is to demonstrate pathology clinical
manifestations of experimental mastitis in dairy cows induced by field isolates of <i>Nocardia farcinica</i>. The
infection was done by intramammary infusion in two healthy lactating dairy cows using two field isolates of
<i>N. farcinica</i>. The infected animals were examined periodically for clinical signs and laboratory profiles. The first
cow showed typical clinical signs of acute <i>Nocardia mastitis</i> with granulomatous reaction whereas the second
cow showed sub-acute clinical mastitis. While the first cow died within a few days post infection, the second
cow survived but didn&#146;t respond to standard mastitis treatment. Treatments of the experimentally induced
mastitis with Neomastipra&reg; and Gentamast&reg; failed to cure the infection and after the withdrawal period of both
drugs <i>Nocardia</i> continued to shed from udder. Clinical isolate of <i>Nocardia farcinica</i> caused mastitis that was
either subacute/irresponsive to treatment or fatal peracute leading to death.
ER  -