TY  - JOUR
T1  - An Assessment of Discriminatory Power of Postmortem Lesions for Diagnosis of
Salmonellosis in Field Condition in Laying Flocks
AU - Uddin, Md. Bashir AU - Kim, Jae-Hoon AU - Mony, Tamanna Jahan AU - Elahi, Fazle AU - Paul, Suman AU - Uddin, Mohammadmejbah AU - Lee, Jong-Soo 
JO  - Journal of Animal and Veterinary Advances
VL  - 16
IS  - 3-7
SP  - 69
EP  - 74
PY  - 2017
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2017.69.74
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2017.69.74
KW  - Salmonellosis
KW  -layer chicken
KW  -post-mortem lesions
KW  -objective diagnosis
KW  -discriminatory power
KW  -approach
AB  - Avian Salmonellosis is considered as one of the major diseases in layer industry. In resource-limited
condition diagnosis of Salmonellosis is based on subjective postmortem examination. Discriminatory power of
this subjective diagnosis has not been systematically examined before. Thus, the present study examined the
discriminatory power of the postmortem lesions for diagnosing Salmonellosis in the layer flocks. Multivariable
diagnostic model based on postmortem lesions was developed to diagnose Salmonellosis in layer
chicken. Post-mortem examinations of 430 dead chickens have been performed of which 138 (32.09%) were
found Salmonellosis positive based on the postmortem lesions. The 17.4% (24 out of 138) of postmortem
suspects were confirmed Salmonella positive by laboratory tests. In univariable analysis enlarged liver, bronze
liver, enlarged spleen, oophoritis, haemorrhage in the intestine and necrotic foci in the liver all produced
a p = 0.1 and were included in the multivariable model. The multivariable diagnostic model was developed using
logistic regression and backward elimination procedure. Enlarged liver, bronze liver, enlarged spleen, oophoritis,
the haemorrhage in the intestine were found significant (p = 0.05) in the final model. Hosmer and Lemeshow
goodness of fit statistics for the final diagnostic model had a p-value estimate of 0.544 which indicates a good
model fit. The area under the ROC curve was 0.826 which shows moderately high diagnostic discriminatory
power. As the postmortem lesions demonstrated a moderately high discriminatory power to differentiate
Salmonella positive birds from negative birds, postmortem lesions based diagnosis of Salmonellosis could be
considered as a useful approach in resource-limited countries where access to the diagnostic laboratory is
limited.
ER  -