TY  - JOUR
T1  - Augmentation Effects of Novel Naringenin Analogues and
Ciprofloxacin as Inhibitors for Nora Efflux Pump (EPIs) and
Pyruvate Kinase (PK) Against MRSA
AU - Mohammed, N.H. AU - Mostafa, Mohamed I. AU - AL-Taher, A.Y. 
JO  - Journal of Animal and Veterinary Advances
VL  - 14
IS  - 13
SP  - 386
EP  - 392
PY  - 2015
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2015.386.392
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2015.386.392
KW  - Naringenin analogues
KW  -pyruvate kinase
KW  -NorA efflux pump
KW  -MRSA
AB  - New naringenin derivatives bearing halogen moiety (1-6) were designed and synthesized. The
structure of the newly synthesized compounds was elucidated by elemental analyses and spectral data. The
in-vitro antimicrobial activity of the obtained compounds has been evaluated. All new analogues tested show
inhibitory activity against microorganisms under investigation, the most potent compounds are 1-4. The rest
of compounds show nearly same antimicrobial activity as ciprofloxacin reference drug used in this study. The
new analogues showed also augmentation effect when used together with ciprofloxacin.
ER  -