TY  - JOUR
T1  - The Differences of Serum IFN-β and Antibodies Concentrations in Chickens at Early and Late ALV-J Infection Stage
AU - Wang, Yan AU - Yin, Yue AU - Lan, Xi AU - Tian, Kai AU - Li, Tian-Jie AU - Zhu, Qing AU - Liu, Yi-Ping AU - Zhao, Xiao-Ling AU - Yin, Hua-Dong AU - Hu, Yao-Dong 
JO  - Journal of Animal and Veterinary Advances
VL  - 13
IS  - 15
SP  - 930
EP  - 936
PY  - 2014
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2014.930.936
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2014.930.936
KW  - ALV-J
KW  -IFN-B
KW  -immunoglobulin
KW  -ALV-J infection stage
KW  -chicken
AB  - Interferon-β (IFN-β) and immunoglobulin M (IgM), 
  immunoglobulin G (IgG) are essential in anti-retrovirus progress. ALV-J is a 
  kind of ubiquitous retrovirus in chicken. To investigate whether natural Avian 
  Leukosis Virus strain J (ALV-J) infection has effect on the concentrations of 
  serum IFN-β, IgM and IgG, two important time points after hatching, 3 and 
  18 weeks age which represent the early and late stages of ALV-J infection, respectively 
  were decided to study. The results reveal that the serum IFN-β, IgM and 
  IgG increase at the early stage of ALV-J infection while decrease at the late 
  stage compared with the control chickens which indicate that ALV-J infection 
  boosts the immune response and up-regulates IFN-β and antibody while long-term 
  infection suppresses immune function and down-regulates IFN-β and antibody.
ER  -