TY  - JOUR
T1  - GHR in Sheep Skin’s Localization and Related Function Research
AU - Zhao, Zongsheng AU - Jia, Chunyang AU - Hu, Hailong AU - Mu, Yanjun AU - Li, Zhimian AU - Li, Qingfeng 
JO  - Journal of Animal and Veterinary Advances
VL  - 13
IS  - 6
SP  - 416
EP  - 422
PY  - 2014
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2014.416.422
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2014.416.422
KW  - Growth hormone receptor
KW  -RT-PCR
KW  -organization in situ hybridization
KW  -sheep
KW  -hair-follicle
AB  - The abundance of GHR (Growth Hormone Receptor) expression and the expression spot in the sheep skin were researched by using relative quota RT-PCR and the organization in situ hybridization. The mRNA level of GHR in the epilated group skin obviously went down in 0th-3rd days and rose to the level before the epilating again in the 6th day. There were not obvious changes in the later. Compared with the control group there was no obvious changes. Though, GHR mRNA in the epilated group obviously was lower than the control group in the 3rd day. But the hybridization signal demonstrated that the closest spot is hair-follicle’s wool nipple and exterior and interior root-sheath on the cut sheet. The dermis and various kinds of different cuticle cells have the very weak hybrid signal or not have. GHR has effect on the hair-follicle cell and it is possibly related to the wool character regulation.
ER  -