TY  - JOUR
T1  - Expression Analysis of Androgen Receptor Transcript Variant 2 (AR2) in Beagle Dog Tissues
AU - Hao, Weidong AU - Wang, Wanyi AU - Mathialagan, Nagappan AU - Fermini, Bernard 
JO  - Journal of Animal and Veterinary Advances
VL  - 13
IS  - 3
SP  - 165
EP  - 170
PY  - 2014
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2014.165.170
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2014.165.170
KW  - Androgen receptor
KW  -transcript variant
KW  -alternative splicing
KW  -beagle dog
KW  -liver
AB  - An N-terminal truncated Androgen Receptor transcript variant 
  2 (AR2), lacking transcription activation domain has recently been identified 
  in human and old world monkeys. The present study was designed to investigate 
  whether corresponding AR2 variant mRNA is expressed in canine tissues. Alignment 
  of human and canine genome AR sequences revealed 81% identity of the AR2 variant 
  specific exon 1B in the canine genome sequence. A conserved 20 bp primer was 
  designed for PCR amplification of canine AR2. By using Reverse Transcription-PCR 
  analysis of RNA from multiple beagle dog tissues, researchers demonstrated the 
  AR2 expression in dogs. Canine AR2 variantm RNA expression was observed in liver, 
  kidney, heart and skeleton muscle suggesting a greater importance to investigate 
  the role of AR2 in the physiological and pathological processes.
ER  -