TY  - JOUR
T1  - Use of Power Doppler for the Assessment of Vascularization in Equine Tendinitis Treated with Mesenchymal Stem Cells
AU - Carvalho, Armando de M. AU - Alvarez, Luis E.C. AU - Oliveira, Patricia G.G. AU - Vendruscolo, Cynthia P. AU - Moroz, Andrei AU - Deffune, Elenice AU - Hussni, Carlos A. AU - Alves, Ana Liz G. 
JO  - Journal of Animal and Veterinary Advances
VL  - 13
IS  - 1
SP  - 15
EP  - 20
PY  - 2014
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2014.15.20
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2014.15.20
KW  - Superficial digital flexor tendon
KW  -tendinitis
KW  -neovascularization
KW  -power Doppler ultrasonography
KW  -MSCs
AB  - Tendinous lesions are very common in athlete horses. The process 
  of tendon healing is slow and the quality of the new tissue is often inferior 
  to the original, leading in many cases to recurrence of the lesion. One of the 
  main reasons for the limited healing capacity of tendons is its poor vascularization. 
  At present, cell therapy is used in equine practice for the treatment of several 
  disorders including tendinitis, desmitis and joint disease. However, there is 
  little information regarding the mechanisms of action of these cells during 
  tissue repair. It is known that Mesenchymal Stem Cells (MSCs) release several 
  growth factors at the site of implantation, some of which promote angiogenesis. 
  Comparison of blood flow using power Doppler ultrasonography was performed after 
  the induction superficial digital flexor tendon tendinitis and implantation 
  of adipose tissue-derived MSCs in order to analyze the effect of cell therapy 
  on tendon neovascularization. For quantification of blood vessel histopathological 
  examinations were conducted. Increased blood flow and number of vessels was 
  observed in treated tendons up to 30 days after cell implantation, suggesting 
  promotion of angiogenesis by the cell therapy.
ER  -