TY  - JOUR
T1  - Determination of Esptein-Barr Virus in the Plasma of Adult Patients with Otitis Media with Effusion
AU - Dong, Yihan AU - Liu, Peng AU - Wei, Xiaoli AU - Su, Kaiming 
JO  - Journal of Animal and Veterinary Advances
VL  - 12
IS  - 1
SP  - 81
EP  - 84
PY  - 2013
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2013.81.84
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2013.81.84
KW  - Esptein-Barr virus
KW  -otitis media with effusion
KW  -real-time fluorescent quantitative PCR
KW  -sympoms
KW  -male
KW  -female
KW  -China
AB  - To investigate the epidemiological characteristics of the 
  Esptein-Barr Virus (EBV) in Otitis Media with Effusion (OME) and its role in 
  the pathogenesis of OME. The plasma samples of 65 patients with OME and 70 healthy 
  people were tested for EBV by real-time quantitative PCR technique. Genomes 
  of EBV positive rate in OME patients are 38.5% (25/65) while only 2.8% (2/70) 
  in control group (p = 0.0001). EBV infection rate in patients with B type tympanogram 
  is higher than that of C type (p = 0.006). No difference of EBV-DNA infection 
  rate was found between the male and female (p = 0.5) or patients with unilateral 
  and bilateral OME (p = 0.076). According to the treatment effect grouping, the 
  EBV infection rate is 17.5% in patients with the subjective symptoms disappeared 
  in three months after treatment, significant lower than that not disappeared 
  or worsen in 3 months (72%, p = 0.001). EBV infection may contribute as a cause 
  of OME and seems to affect the treatment effect. More extensive study are required 
  to elucidate the role of the EBV and the relationship of OME.
ER  -