TY  - JOUR
T1  - A Novel PCR-RFLP (Xba I) Polymorphism Analysis of the Bovine Calpastatin (<I>CAST</I>) Gene in Chinese Luxi Cattle
AU - Yang, Dongying 
JO  - Journal of Animal and Veterinary Advances
VL  - 12
IS  - 6
SP  - 788
EP  - 790
PY  - 2013
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2013.788.790
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2013.788.790
KW  - Genetic polymorphisms
KW  -CAST gene
KW  -haplotype
KW  -RFLP
KW  -cattle
AB  - Calpastatin (CAST) is a specific inhibitor of the ubiquitous 
  calcium-dependent proteases-&#956;-calpain and m-calpain, found in mammalian 
  tissues. In the coding region of the bovine <I>CAST</I> gene (CAST) the new 
  nucleotide sequence polymorphism was found being a substitution G&rarr;C at position 
  962 nt (consensus sequence-GenBank AF281256). Consensus of bovine CAST sequence 
  with that of human revealed that G&rarr;C substitution was located at position 1460 
  nt of exon 12. Computer analysis of the mutation showed the Ser&rarr;Thr substitution 
  for CAST protein. The frequency of alleles C and G was 0.41 and 0.59, respectively. 
  The message from these results is that <I>CAST</I> gene may probably be considered 
  as a candidate marker for beef quality.
ER  -