TY  - JOUR
T1  - Screening of Ginseng Proteins Interacted with BVDV E0 Protein
AU - Zhao, Xueliang AU - Gao, Yugang AU - Zang, Pu AU - Yang, He AU - Liu, Tong AU - Liu, Qun AU - Zhang, Lianxue 
JO  - Journal of Animal and Veterinary Advances
VL  - 12
IS  - 6
SP  - 699
EP  - 704
PY  - 2013
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2013.699.704
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2013.699.704
KW  - Bovine viral diarrhea virus
KW  -ginseng
KW  -yeast two hybrid
KW  -cDNA library
KW  -reproductive disorder
AB  - Bovine Viral Diarrhea Virus (BVDV), a single-stranded RNA 
  virus can cause fatal diarrhoea syndrome, respiratory problems and reproductive 
  disorder in herd. However, there still no effective vaccine or medicines for 
  controlling the spreading of BVDV. In this study, researchers are interested 
  in obtaining proteins with anti-BVDV activity in ginseng. The structure protein 
  E0 of BVDV was used as bait protein to screen the ginseng cDNA library by the 
  yeast two hybrid assay system. The result showed that eukaryotic translation 
  initiation factor 5A (eIF5A) of ginseng has direct interaction with E0. The 
  interaction was verified by GST-pull down analysis. This interaction provides 
  a target for researching of antiviral drugs for controlling the spreading of 
  BVDV.
ER  -