TY  - JOUR
T1  - Effect of Chinese Medicine Effective Component Prescription of Chickens Immune Organ CD4+, CD8+ After IBDV Infected
AU - Shi, Qiumei AU - Gao, Guisheng AU - , Guangping Gao AU - , Yanying Zhang AU - , Jianzhong Xu AU - , Ping Shen 
JO  - Journal of Animal and Veterinary Advances
VL  - 12
IS  - 5
SP  - 660
EP  - 663
PY  - 2013
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2013.660.663
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2013.660.663
KW  - Chinese medicine effective component
KW  -IBDV
KW  -immunomodulator
KW  -CD4+
KW  -CD8+
AB  - To elucidate the pharmaceutical mechanism about the prevention 
  and treatment effects of Zihuangsan, so as to provide theoretical basis on animal 
  production. The 240, 1 day old chickens were acclimatized for 6 days and then 
  randomly divided into groups A, B, C, D, E and F, 40 birds in each group. The 
  birds in group A, B and C were administered with three dose such as high, middle 
  and low of Chinese Medicine Prescription-Zihuangsan. The chickens in groups 
  D, E and F were given with the same volume of Normal Saline (NS). The birds 
  in groups A, B, C, D and E were infected with IBDV by eye drop, group F as normal 
  control by using NS instead of IBDV and Zihuangsan. The 3 days after IBDV infected, 
  0.5 mL yolk antibody per bird in group D was given intramuscularly. Result show 
  Zihuangsan could significantly reduce the chicken’s 
  mortality and increase the development of positive expression of CD4+, CD8+ 
  T in immune organs such as thymus and intestinal. Zihuangsan could regulate 
  the immune deficiency caused by IBDV. The best dosage of Zihuangsan is middle 
  dose.
ER  -