TY  - JOUR
T1  - Anti-Fatigue Activity of Crude Saponins from <I>Panax quinquefolium</I>
AU - Jin-Ming, Xing AU - , Yuan Wen-Xue AU - , Zhang Zhi-Cheng AU - , Chen Shuai 
JO  - Journal of Animal and Veterinary Advances
VL  - 12
IS  - 5
SP  - 584
EP  - 588
PY  - 2013
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2013.584.588
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2013.584.588
KW  - Anti-fatigue activity
KW  -crude saponins from Panax quinquefolium
KW  -forced swimming test
KW  -mice
KW  -liver glycogen
AB  - The present study was carried out to investigate anti-fatigue 
  activity of Crude saponins from <I>Panax quinquefolium </I>(CPQS) in mice. The 
  animals were randomly divided into four groups: control (distilled water); 50 
  mg kg<SUP>-1</SUP> CPQS; 100 mg kg<SUP>-1</SUP> CPQS and 200 mg kg<SUP>-1</SUP> 
  CPQS. Distilled water or CPQS were orally administered for consecutive 28 days. 
  The 28 days later, forced swimming test was performed and then fatigue-related 
  biochemical parameters including blood lactic acid, serum urea nitrogen, liver 
  glycogen and muscle glycogen were detected. The results showed that CPQS could 
  prolong the swimming to exhaustion time of mice as well as increasing the liver 
  and muscle glycogen contents but decrease the blood lactic acid and serum urea 
  nitrogen levels. Therefore, the present study demonstrated that CPQS possessed 
  anti-fatigue activity.
ER  -