TY  - JOUR
T1  - Expression and Changes of Visfatin in the Intestinal Mucosal of LPS-Induced Piglets
AU - Song, H. AU - Xiao, K. AU - Zhu, X. AU - Peng, K.M. AU - Wang, N. 
JO  - Journal of Animal and Veterinary Advances
VL  - 12
IS  - 19
SP  - 1484
EP  - 1488
PY  - 2013
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2013.1484.1488
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2013.1484.1488
KW  - Visfatin
KW  -
KW  -LPS
KW  -small intestinal mucosa
KW  -expression changes
KW  -tissue
AB  - The purpose of this study was to elucidate the function of visfatin in the 
  mucosal immune barrier of weaned piglets by observing histological changes in 
  the small intestine and visfatin expression in LPS-induced piglets. The mucosal 
  structure of the small intestine was damaged. The duodenum, jejunum, ileum and 
  the intestinal villous were atrophied and shorter. Epithelial lymphocytes and 
  lamina propria lymphoid tissue was reduced and aggregates of lymphoid nodules 
  were increased. Visfatin-positive products were expressed in the small intestinal 
  mucosa and mainly distributed in lamina propria lymphoid tissue. After LPS administration, 
  visfatin-positive cells were reduced in the epithelial lymphocytes, lamina propria 
  and intestinal gland but increased in aggregates lymphoids. This study suggested 
  that an LPS-induced immune stress model could induce structural changes of piglet 
  small intestine and cause changes of intestinal mucosal immune barrier function. 
  In addition, the distribution and quantity of visfatin-positive cells were altered, 
  suggesting visfatin is involved in the humoral immune responses of piglets.
ER  -