TY  - JOUR
T1  - The Effects of Vaccination on the Immune Responses of Dairy Cattle Seropositive to Bovine Viral Diarrhea Virus (BVDV)
AU - Mamak, Nuri AU - Hasircioglu, Sibel AU - Gokce, Halil Ibrahim AU - Yavru, Sibel AU - Kale, Mehmet AU - Yildiz, Ramazan AU - Avci, Oguzhan AU - Bulut, Oya AU - Yapici, Orhan AU - Simsek, Atilla 
JO  - Journal of Animal and Veterinary Advances
VL  - 12
IS  - 13
SP  - 1151
EP  - 1155
PY  - 2013
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2013.1151.1155
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2013.1151.1155
KW  - Bovine viral diarrhea virus
KW  -seropositive
KW  -seronegative
KW  -vaccination
KW  -dairy cattle
AB  - The aim of the study was to determine the effects of vaccination 
  on the antibody titres of dairy cattle seronegative and seropositive to Bovine 
  Viral Diarrhea Virus (BVDV). For this purpose, 23 cattle were used in the study. 
  Before the vaccination, 23 cattle from two different dams (consisted of 15 and 
  8 in each) were tested for presence of BVDV specific antibodies and antigens. 
  In the study, 16 (69.6%) and 2 (8.7%) animals were found to seropositive and 
  persistently infected [antigen (+) but antibody (-)], respectively. Remaining 
  5 cattle (21.7%) were detected as seronegative. Sixteen seropositive and five 
  seronegative cattle were vaccinated with an inactive commercial BVDV vaccine. 
  In the study, serum and blood samples were collected before and after vaccination 
  and analysed for the precence of BVDV specific antibodies and antigens using 
  Enzyme Linked Immunosorbent Assay (ELISA). Serum Neutralization Test (SNT) was 
  also used to detect BVDV neutralizing specific antibodies. Antibody titres in 
  serum samples collected from vaccinated seropositive animals were significantly 
  (p = 0.001, p<0.001) increased compare to those of samples collected before 
  vaccination detected by ELISA. Finally, it was thought that vaccination of seropositive 
  cattle for BVDV may result in long-lasting and strong immunity compared to those 
  of seronegative animals which may benefical to protect cattle against BVDV infection.
ER  -