TY  - JOUR
T1  - Polymorphism of Ovar-DRB1 Second Exon with PCR-RFLP Technique in Arabi Sheep Population of Khuzestan Province
AU - Lotfi, Mojtaba AU - , Mohammad Taghi Beigi Nassiri AU - , Hedayatollah Roshanfekr AU - , Jamal Fayazi 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 6
SP  - 760
EP  - 762
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.760.762
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.760.762
KW  - Arabi sheep
KW  -MHC
KW  -Ovar-DRB1
KW  -PCR-RFLP
KW  -Khuzestan province
KW  -Iran
AB  - Major Histocompatibility Complex (MHC) plays a pivotal role in antigen presentation for eliciting immune responses against invading pathogens. The best characterized genetic control of disease resistance and immune response in animals are associated with MHC. Therefore, in this study polymorphism of Ovar-DRB1 in DNA samples of 111 heads Arabi sheep using Polymerase Chain Reaction (PCR) and Restriction Fragment Length Polymorphism (RFLP) method was examined. Identities of 18 different patterns and 8 distinct DRB1 alleles among Arabi sheep have been determined. There is not deviation in <I> Ovar-DRB1</I> gene from Hardy-Weinberg equilibrium in this population, results showed. Obtained results have revealed that the exon 2 region of Ovar-DRB1 was highly polymorphic on Arabi sheep.
ER  -