TY  - JOUR
T1  - Effect of Amantadine on Serumic Levels of ALT, AST and ALP in Native Poultry
AU - Mirhadi, Khayatnouri AU - Alireza, Yagoobnegad AU - Saeid, Safarmashaei 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 1
SP  - 64
EP  - 66
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.64.66
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.64.66
KW  - Amantadine
KW  -poultry
KW  -ALT
KW  -AST
KW  -ALP
KW  -Iran
AB  - Clinical trials have documented that amantadine hydrochloride is effective drug for the prophylaxis and treatment of influenza A virus infection. Newsday use of amantadine for treatment of influenza has been increased. The aim of present study was to determine the effect of Amantadine on serumic levels of ALT, AST and ALP in native poultry. About 10 adult hens weighing between 2 and 2.5 kg were used for the study. In first steps one blood sample were taken. In secondary steps amantadine (orally) with dose of 25 mg kg<SUP>-1</SUP> for 4 consecutive weeks were administrated. Blood samples in days of 1, 3, 7, 14, 21 and 28 after administration from every hen were taken and after centrifugation serums for seral titration of ALT, AST and ALP by standards kits were used. In fact study according to results of present study a significance in serumic levels of AST in 21, 28 and ALP in 3 , 7, 14, 21, 28 after orally amantadine administration were observed.
ER  -