TY  - JOUR
T1  - Analysis of the Effect of Virulent Marek&#146;s Disease Virus <I>SORF2</I> 
  Gene on its Horizontal Transmission Capacity Using Real-Time PCR
AU - Su, Shuai AU - Cui, Ning AU - Wang, Yixin AU - Sun, Aijun AU - Qi, Pengfei AU - Chen, Zimeng AU - Zhao, Peng AU - Cui, Zhizhong 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 24
SP  - 4648
EP  - 4654
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.4648.4654
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.4648.4654
KW  - Marek`s disease virus
KW  -SORF2 gene
KW  -horizontal transmission capacity
KW  -real-time PCR
KW  -China
AB  - Marek&#146;s Disease Virus (MDV) Chinese strain GX0101 was 
  the first reported recombinant MDV field strain with one Reticuloendotheliosis 
  Virus (REV) Long Terminal Repeat (LTR) insert. REV LTR in the GX0101 genome 
  increased the potential for horizontal transmission. REV LTR fragment has the 
  biggest impact on <I>SORF2</I> gene. Researchers detected the influence of <I>SORF2</I> 
  gene deletion on its horizontal transmission ability by real time PCR. The result 
  shows that GX0101&#916;Sorf2 possesses similar replication ability with bac-GX0101 
  no mater on the level of lymphocyte or feather follicle. Although, researchers 
  can detect MDV positive in feather follicles of sentinel in contact chickens 
  at age 10 in both groups respectively, the number of SPF chickens infected with 
  bac-GX0101 by contact is higher than the number of GX0101&#916;Sorf2 infection 
  group. Therefore, <I>SORF2</I> gene has certain effect on the horizontal transmission 
  ability of the virus.
ER  -