TY  - JOUR
T1  - Observation on Viral Variation and Vaccine Development in Marek’s Disease in China
AU - Gong, Zhenhua AU - Wang, Liping AU - Hu, Yonghao AU - Lu, Ping AU - Zhang, Lijuan AU - Li, Weihua 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 24
SP  - 4611
EP  - 4614
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.4611.4614
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.4611.4614
KW  - vaccine
KW  -viral variation
KW  -Marek`s disease
KW  -epidemic
KW  -evolution
AB  - Marek’s Disease (MD) is one of the main infectious diseases 
  that threaten the healthy development of the Chinese poultry industry. The evolution 
  of epidemic strains of the MD Virus (MDV) in China is different from the evolution 
  of strains overseas. The <I>meq</I> gene sequence of pathogenic strains is different 
  from that of the attenuated vaccine strain (MDV-1). The <I>meq</I> and <I>L-meq</I> 
  gene sequences of the MDV in the lymphoid tissue of chickens in latency period 
  are homologous. The <I>meq</I> gene was only found in the lymphoid tissue of 
  chickens during the onset period.
ER  -