TY  - JOUR
T1  - A Systematic Review of Endothelial Colony-Forming Cells
AU - Hu, Lin-Sen AU - Liu, Zhi-Qiang AU - Li, Da-Wei AU - Zang, Zhao-Xia AU - Chang, Ming 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 24
SP  - 4506
EP  - 4513
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.4506.4513
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.4506.4513
KW  - Endothelial colony-forming cells
KW  -endothelial progenitor cells
KW  -neovascularization
KW  -hierarchy
KW  -expansion
AB  - Endothelial Progenitor Cells (EPCs) may play a crucial role 
  in postnatal vasculogenesis which contribute to the development of vascular 
  biology. So far, there has not a consensus definition of EPCs. In 2004, Ingram 
  developed a single-cell clonogenic assay and identified a unique cell population 
  based on their proliferative potential in human umbilical cord blood and adult 
  peripheral blood and named this cell population as Endothelial Colony-Forming 
  Cells (ECFCs). Accumulating data suggest that ECFCs possess all the characteristics 
  of EPCs including robust clonal proliferative capacity and the ability to form 
  <I>de novo</I> blood vessels with a lumen<I> in vivo</I> and capillary-like 
  tube <I>in vitro</I>. Therefore, ECFCs may be true EPCs and have been highly 
  concerned as a superior type of cells to treat patients with vascular diseases. 
  This review will focus on the characteristics, hierarchy, expansion, functions 
  of ECFCs. Researchers attempt to provide a comprehensive understanding of the 
  cells to promote the development of cell-based therapy for patients suffering 
  from vascular diseases.
ER  -