TY  - JOUR
T1  - Efficacy of Intravenous Administration of Ephedrine for Prevention of Xylazine-Induced Hypotension in Camels (<i>Camelus dromedarius</i>)
AU - Almubarak, A.I. 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 23
SP  - 4460
EP  - 4464
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.4460.4464
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.4460.4464
KW  - Camel
KW  -ephedrine
KW  -xylazine
KW  -hypotension
KW  -haematology
KW  -biochemistry
AB  - The effects of ephedrine on Arterial Blood Pressure (ABP), 
  heart rate, respiratory rate and some haematology and biochemistry parameters 
  were carried out on six camels in two periods. In the first period, all camels 
  received Intravenous (IV) 0.2 mg kg<SUP>-1</SUP> xylazine while in the second 
  period, same camels received IV 0.2 mg kg<SUP>-1</SUP> ephedrine followed 10 
  min later by IV 0.2 mg kg<SUP>-1</SUP> ephedrine and 0.2 mg kg<SUP>-1</SUP> 
  xylazine administered at same time. Cardiopulmonary measurements were taken 
  at baseline and were further recorded at 10, 20, 30, 40, 50 and 60 min after 
  treatment in both groups. Mean heart rate, respiratory rate and ABP measurements 
  decreased significantly after xylazine in the first period. Mean heart rate 
  in the second period decreased significantly at all times compared to baseline 
  and to first period while mean ABP measurements were significantly higher at 
  10, 20, 30 and 40 min compared to first period. There was a significant decrease 
  of Platelet count (PLT), Haemoglobin (HB), Urea Nitrogen (BUN), Albumen (ALB), 
  Alanine aminotransferase (ALT) and Glucose (GLU) in the first period compared 
  to the second period and there was significant increase of Calcium (Ca) and 
  potassium (K<SUP>+</SUP>) after treatments in the second period. Ephedrine was 
  safe and effective in improving ABP in xylazine induced hypotension in camels.
ER  -