TY  - JOUR
T1  - Genes Expression Related to Intramuscular Fat Deposition in Muscles of Small Tail Han Sheep
AU - Zhu, Huabin AU - Liu, Yan AU - Ma, Teng AU - Du, Weihua AU - Hao, Haisheng AU - Wang, Dong AU - Zhao, Xueming AU - Li, Haijing AU - Jiang, Qiuling 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 21
SP  - 3969
EP  - 3977
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.3969.3977
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.3969.3977
KW  - Gene expression
KW  -gluteus maximus
KW  -intramuscular fat
KW  -longissimus dorsi
KW  -muscle
KW  -sheep
AB  - Intramuscular Fat (IMF) is an important factor affecting meat quality. The objective of this study was to investigate the expression changes of genes related to IMF formation in muscles of Small Tail Han sheep. These genes include Acetyl CoA Carboxylase (ACC), Fatty Acid Synthase (FAS), Diacylglycerol Acyltransferase 1 (DGAT1), Heart Fatty Acid Binding Protein (H-FABP), CCAAT-Enhancer-Binding Protein α (C/EBPα), Peroxisome Proliferator-Activated Receptor γ (PPARγ), Malic Enzyme ( ME) and Lipoprotein Lipase (LPL). In the longissimus dorsi, IMF content continuously increased with growth and was significantly different (p<0.05) at all 4 months; however, IMF content reached a maximum at 5 months in the gluteus maximus. The gene expression patterns of the 8 genes involved in IMF synthesis mainly followed one of 2 trends: gene expression tended to be lowest at 4 or 5 months and then subsequently increase in the longissimus dorsi whereas gene expression tended to peak at 4 or 5 months and then subsequently decrease in the gluteus maximus. Intramuscular fat content correlated with the expression levels of all genes in the longissimus dorsi and all genes except DGAT1, H-FABP in the gluteus maximus. Remarkably, all of the above correlations between IMF and gene expression levels were positive. In conclusion, the correlation between gene expression levels and IMF content indicate that these genes play an important role in the deposition of IMF in Small Tail Han sheep.
ER  -