TY  - JOUR
T1  - Applications of Quantitative Serum Neopterin Determination in Dogs Affected by Leishmaniasis-Preliminary Study
AU - Matteo, Cerquetella AU - Daniele, Spaziante AU - Fulvio, Laus AU - Francesca, Beribe AU - Carlotta, Marini AU - Silvia, Preziuso AU - Vincenzo, Cuteri AU - Andrea, Spaterna AU - Beniamino, Tesei 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 21
SP  - 3937
EP  - 3942
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.3937.3942
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.3937.3942
KW  - Neopterin
KW  -dog
KW  -leishmania
KW  -cellular immune response
KW  -disease
KW  -patients
AB  - The aim of the present study was to evaluate possible correlations between Neopterin serum values and Immunofluorescence Antibody Test (IFAT) titers in dogs positive for <I>Leishmania infantum</I> and to provide further reference values for Neopterin in seronegative patients. Neopterin has been determined in 74 dogs, 30 of which where clinically healthy, seronegative and without any particular laboratory abnormalities for the tested parameters while the remaining 44 were positive to IFAT. The heterogeneous results obtained for Neopterin values in seronegative dogs in the present study did not allow inferring reference limits in those subjects but some of the correlations between Neopterin and IFAT titers in seropositive ones encourage further studies on that matter, possibly comparing the molecule values with other traditional markers of infection/disease. The present study represents a possible preliminary step towards the use of serum Neopterin values as a biomarker in dogs affected by leishmaniasis.
ER  -