TY  - JOUR
T1  - Phenotypic Detection and Drug Resistance Analysis of Extended-Spectrum &#946;-Lactamases among <I>Escherichia coli</I> Isolates from Diseased Duck
AU - Hu, Gong-Zheng AU - Wu, Hua AU - Wang, Shan-Mei AU - Pan, Yu-Shan AU - Liu, Bao-Guang AU - He, Zhi-Pei 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 21
SP  - 3870
EP  - 3875
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.3870.3875
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.3870.3875
KW  - Duck
KW  -Escherichia coli
KW  -Extended-Spectrum Beta-Lactamases (ESBLs)
KW  -phenotype
KW  -antibiotics susceptibility
AB  - Thirty two <I>Escherichia coli</I> isolates recovered from diseased ducks diagnosed with colibacillosis in China between 2010 and 2011 were characterized for detection of Extended-Spectrum &#946;-Lactamases (ESBLs) by phenotypic screening and confirmatory test provided by the Clinical Laboratory Standards Institute and antimicrobial susceptibility profiles via agar disk diffusion and a broth doubling dilution method. Results showed 7 of the 32 <I>E. coli</I> isolates analyzed (21.87%) were found to be ESBL producers. The resistant rates of ESBL producers were &gt;28.6% against third generation cephalosporins and semisynthetic penicillins and as high as 100% against amoxicillin, ampicillin and ceftiofur. All 32 isolates were sensitive to imipenem, meropenem and cefepime and the susceptible rates of all 32 isolates to &#946;-lactam antibiotics in combination with enzyme inhibitors were higher than those of &#946;-lactam antibiotics alone. Therefore, ESBL-producing isolates had multi-drug resistance and enzyme inhibitors can partially solve the drug resistance problem.
ER  -