TY  - JOUR
T1  - Polymorphism of Ovar-DRB1 Second Exon with PCR-RFLP Technique in Arabi Sheep Population of Khuzestan Province
AU - Lotfi, Mojtaba AU - Taghi Beigi Nassiri, Mohammad AU - Roshanfekr, Hedayatollah AU - Fayazi, Jamal 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 3
SP  - 343
EP  - 345
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.343.345
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.343.345
KW  - Arabi sheep
KW  -MHC
KW  -ovar-DRB1
KW  -PCR-RFLP
KW  -Khuzestan province
KW  -Iran
AB  - Major Histocompatibility Complex (MHC) plays a pivotal role in antigen presentation for eliciting immune responses against invading pathogens. The best-characterized genetic control of disease resistance and immune response in animals are associated with MHC. Therefore in this study polymorphism of ovar-DRB1 in DNA samples of 111 heads Arabi sheep using Polymerase Chain Reaction (PCR) and Restriction Fragment Length Polymorphism (RFLP) method was examined. Identities of 18 different patterns and 8 distinct DRB1 alleles among Arabi sheep have been determined. There is not deviation in <I> Ovar-DRB1</I> gene from Hardy-Weinberg equilibrium in this population results showed. Obtained results have revealed that the exon 2 region of ovar-DRB1 was highly polymorphic on Arabi sheep.
ER  -