TY  - JOUR
T1  - The Light Microscopic Study of Age-Associated Changes in Dog Synovial Membrane 
  Cells
AU - Oya Sagiroglu, Ayse 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 18
SP  - 3369
EP  - 3377
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.3369.3377
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.3369.3377
KW  - Dog synovial membrane
KW  -age-associated changes
KW  -intimal lining cells
KW  -fibroblasts
KW  -mast cells
KW  -lymphocytes
KW  -plasma cells
AB  - Age associated structural changes in the synovial membrane cells were studied in 24 Kangal hybrid-breed dogs. Dogs were grouped in 3 age groups young, middle aged and old. Synovial intima were made of 1-2 layered flat and oval intimal cells in the young group dogs and 3-5 to 2-6 multi-layered cubic and polygonal lining cells in the middle aged and the old dogs. Continuous villi were not present in all the age groups and therefore, it was not possible to determine any change in the amounts of villi in different age groups. Subintima changed from areolar, adipose, areola-adipose and fibrous connective cells, from young to old group dogs. Fibroblasts and various connective tissue cells of the young dogs placed in the deep layers of the subintima. Lymphocytes and plasma cells occurred in the environs of blood vessels. Various connective tissue cells concentrated among the collagen fibers and collagen bundles in the vicinity of blood vessels in middle aged group dogs. In the old group dogs, connective tissue cells decreased in subintima and placed among collagen and elastic fibers.
ER  -