TY  - JOUR
T1  - Intrarenal Artery Autologous Mesenchymal Stem Cell Injection for Treatment of Chronic Glomerulonephritis in Cat
AU - Hsuuw, Yan-Der AU - Lin, Sheng-Chuan AU - Kuo, Tzong-Fu AU - Huang, Fu-Jen AU - Chang, Tsung-Chou 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 16
SP  - 3019
EP  - 3022
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.3019.3022
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.3019.3022
KW  - Chronic glomerulonephritis
KW  -chronic kidney diseases
KW  -mesenchymal stem cells
KW  -stem cell therapy
KW  -uremia
AB  - Chronic glomerulonephritis is a major cause of morbidity and mortality in feline chronic kidney diseases. Mesenchymal stem cells are multipotent stem cells found in the stroma of bone marrow, adipose tissue and umbilical cord. Mesenchymal stem cells can be induced to differentiate into a wide array of cells types including osteoblasts, chondrocytes, myocytes, adipocytes, endothelium and neuronal cells. The effects of mesenchymal stem cell therapy have been investigated in rodent chronic renal failure models including genetic disease, glomerulo-nephritis and experimentally-induced chronic kidney diseases. The purpose of this study was to assess the feasibility of intra-renal artery mesenchymal stem cells transfer in cat with chronic glomerulo-nephritis. Researchers, hypothesized that mesenchymal stem cells could be safely administered to cats with chronic glomerulo-nephritis. Intra-renal artery mesenchymal stem cells injection would improve the function of the injected kidney. This clinical result showed the optimal direction that the patient demonstrated blood urea nitrogen and creatinine improvement after intra-renal artery mesenchymal stem cells transfer.
ER  -