TY  - JOUR
T1  - Effects of Oral Supplementation with N-Carbamylglutamate on Serum Biochemical Indices and Intestinal Morphology with its Proliferation in Weanling Piglets
AU - Ying, Peng 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 16
SP  - 2926
EP  - 2929
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.2926.2929
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.2926.2929
KW  - N-carbamylglutamate
KW  -arginine
KW  -mucosal morphology
KW  -piglets
KW  -proliferation
AB  - The experiment was conducted to evaluate the effects of N-Carbamylglutamate (NCG) on intestinal mucosa with its proliferation in weanling piglets. About 12 Duroc x Landrace x Yorkshire piglets (average BW 5.67±0.14 kg; weaned at 21 days) were grouped into 2 treatments and fed one of the following diets for 7 days: a Standard Diet (SD), SD+NCG (0.05%). All the piglets were sacrificed for blood and tissue collection. The results showed that compared with the control group, NCG decreased serum urea nitrogen and ammonia concentration (p<0.05). Adding NCG to the diet resulted in a higher villus height in jejunum (p<0.05). The RT-PCR results showed that NCG significantly increased PCNA mRNA abundance in both jejunum (p<0.05) and ileum (p<0.01). These results indicated that oral supply of NCG improved intestinal mucosa morphology and had favorable effects on proliferation of intestinal mucosa.
ER  -