TY  - JOUR
T1  - Clinicopathological Effects of Various Levels of Dietary <I>Ambrosia maritima</I> on Wistar Rats
AU - Bakheit, A.O. AU - Barakat, S.E.M. AU - Al-Hizab, F.A. 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 15
SP  - 2672
EP  - 2676
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.2672.2676
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.2672.2676
KW  - Ambrosia maritima
KW  -clinicopathology
KW  -hepatotoxicity
KW  -enteritis
KW  -serum
KW  -body weight
AB  - The present study deals with the clinicopathological and biochemical 
  effect of <I>A. maritima</I> on male Wistar rats. <I>Ambrosia maritime</I> is 
  claimed to have several medicinal properties and used as a traditional medicine 
  for the treatment of various disorders. The plant was fed to rats at 2 and 10% 
  of the standard diet for 4 weeks. A 2% <I>A. maritima</I> was not toxic to rats 
  during the experiment. However, mild increase in body weight, fatty cytoplasmic 
  vacuolation, centrolobular individual cell necrosis and mild enteritis were 
  observed in rats fed a diet containing 10% <I>A. maritima</I>. These findings 
  were accompanied by alteration of serum Aspartate aminotransferase (AST), Alanine 
  aminotransferase (ALT) and no changes were observed in the activities of ALP, 
  concentrations of total protein, urea, total bilirubin, HDL and LDL. The concentrations 
  of cholesterol and glucose were significantly decreased in the serum of rats 
  fed 2 and 10% <I>A. maritima</I>.
ER  -