TY  - JOUR
T1  - Cryotherapy Combined with Warm Transfusion Apply to Serious Burns in a Rabbit Model: An Experimental Study
AU - Lv, Chunliu AU - Zhang, Pihong AU - Huang, Xiaoyuan AU - Zeng, Jizhang AU - Ren, Licheng AU - Liang, Pengfei 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 15
SP  - 2641
EP  - 2646
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.2641.2646
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.2641.2646
KW  - Burns
KW  -cryotherapy
KW  -core body temperature
KW  -warm transfusion
KW  -rabbits
AB  - This study investigated the effect of cryotherapy combined 
  with warm transfusion on vital signs, inflammatory response and tissues permeability 
  in rabbits with severe burns. Rabbits were subjected to deep partial-thickness 
  scald covering of 40% Total Body Surface Area (TBSA). Rabbits were randomly 
  divided into 4 groups namely scald group (A), cryotherapy after scald group 
  (B), warm transfusion after scald group (C), group of cryotherapy combined with 
  warm transfusion after scald (D). Cryotherapy meant soaking the burn wound in 
  10°C cold water for 40 min after scald 5 min. Fluid of warm transfusion 
  was maintained at 39. This data shown that cryotherapy decreased the core body 
  temperature, Mean Arterial Pressure (MAP) and wound Myeloperoxidase (MPO) activity 
  in rabbits and increased the levels of reduced shear viscosity/erythrocyte aggregation 
  and inflammatory mediators compared to control group. The upper indicators produced 
  the opposite changes under warm transfusion. Moisture content of lung in group 
  C and moisture content of wound in group B were lower compared to group A. Moreover, 
  burn wound MPO, moisture content of lung and wound and inflammatory mediators 
  significantly descended in group D.
ER  -