TY  - JOUR
T1  - Dietary Supplementation with Recombinant Lactoferrampin-Lactoferricin Improves Growth 
  Performance and Affects Serum Parameters in Piglets
AU - Yin, Yulong AU - Tang, Xiangshan AU - A. Fatufe, Andrew AU - Tang, Zhiru AU - Wang, Shengping AU - Liu, Zhiqiang AU - , Xinwu AU - Li, Tie-Jun 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 14
SP  - 2548
EP  - 2555
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.2548.2555
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.2548.2555
KW  - Antimicrobial peptide
KW  -bovine lactoferrampin-lactoferricin
KW  -growth performance
KW  -piglet
KW  -China
AB  - Up to thirty piglets with an average live body weight of 5.9&plusmn;0.5 kg were challenged using enterotoxigenic<I> Escherichia coli</I> and randomly assigned to three treatment groups fed a corn-soybean meal-based diet containing either no addition (control group), 0.1 g kg<SUP>-1</SUP> of lactoferrampin-lactoferricin (lactoferrampin-lactoferricin group) or 0.1 g kg<SUP>-1</SUP> of chlortetracycline (chlortetracycline group) for 21 days. Compared with the control group, dietary supplementation with lactoferrampin-lactoferricin or chlortetracycline increased the body weight and daily weight gain and decreased the feed to gain ratio, diarrhea rate and serum IgM and IgG levels (p&lt;0.05). The serum levels of IL-1&#946;, IL-6, TNF-&#945;, diamine oxidase and endothelin-1 were not significantly different among all treatment groups (p&gt;0.05). Compared with the control group, dietary supplementation with lactoferrampin-lactoferricin changed the serum concentrations of 10 amino acids (p&lt;0.05); dietary supplementation with chlortetracycline only changed the serum histidine concentration (p&lt;0.05). These results indicate that lactoferrampin-lactoferricin and chlortetracycline have similar effects on piglets weaned at 21 days of age which is expected to have practical applications in the livestock industry.
ER  -