TY  - JOUR
T1  - Effects of Grape Seed Extract on Renal Ischemic Reperfusion in Rats
AU - Hashemi, Mehrdad AU - Ashrafadin Goushegir, Seyed AU - Doustar, Yousef AU - Hashem Dabaghian, Fataneh 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 14
SP  - 2529
EP  - 2532
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.2529.2532
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.2529.2532
KW  - lipid
KW  -apoptosis
KW  -grape seeds extract
KW  -Ischemic reperfusion
KW  -protection
KW  -Iran
AB  - Grape Seed Extract (GSE) has been reported to exert protective effects on various forms of renal ischemic reperfusion disorders. Natural Grape Seed Extract (GSE) are potent free radical scavengers and hence, provide significant protection against oxidative stress. Accordingly, the present study focused on investigating the possible protective role of GSE against ischemic reperfusion mediated damage in renal tissues in rats. The results revealed that oral administration of 250 mg kg<SUP>-1</SUP> (body weight) of GSE for 3 days significantly protect against renal cell apoptosis via the induction of endogenous antioxidant (p&lt;0.001).
ER  -