TY  - JOUR
T1  - Protective Effect of Corn Oligopeptides on Acute Alcoholism in Rodent Models
AU - Li, Yong AU - Zhang, Feng AU - Zhang, Jiali AU - Xu, Meihong AU - Dai, Xiaoqian AU - Li, Yujie AU - Ding, Ye AU - Zhang, Zhaofeng 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 12
SP  - 2070
EP  - 2074
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.2070.2074
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.2070.2074
KW  - Acute alcoholism
KW  -corn oligopeptides
KW  -ethanol
KW  -protective effect
KW  -control group
AB  - The present study aimed to investigate the effects of Corn Oligopeptides (COP) on acute alcoholism in rat models. Female SD rats were randomly assigned to 4 groups per test including control group and 3 COP intervention groups (2.25, 4.5 and 9 g/kg/BW). About 5 g/kg/BW ethanol (8 g/kg/BW for loss of righting reflex test) was given intragastricly 10 min before COP treatment. Ethanol levels in blood, behavioral studies and ADH activity in liver were assayed. Researchers found that COP treatment could promote the alcohol metabolism and correct the movement disorder caused by alcohol consumption to some extent. However, the ADH levels had no changes among different groups. These findings suggest that COP have a protective effect on acute alcoholism in rats.
ER  -