TY  - JOUR
T1  - Promoter Characterization and Expression Pattern Analysis of Porcine <I>TCAP</I> Gene
AU - Mei, Shuqi AU - Liu, Guisheng AU - Peng, Xianwen AU - Wu, Huayu AU - Qiao, Mu AU - Huang, Jingshu AU - Feng, Zheng 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 11
SP  - 1876
EP  - 1880
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.1876.1880
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.1876.1880
KW  - China
KW  -TCAP
KW  -promoter
KW  -Porcine
KW  -bioinformatics
AB  - TCAP is one of the titin interacting Z-disc proteins involved in the regulation and development of normal sarcomeric structure. In this study, researchers cloned the 5' upstream region of porcine <I>TCAP</I> gene. Bioinformatic analysis of the 5' regulatory region has revealed that in addition to several ubiquitous transcription factors binding sites (SP1, AP1 and C/EBP) were found, several putative muscle-specific transcription factor binding sites (MyoD, MyoG and MEF2) were present in this region. Tissue expression analysis showed that the porcine <I>TCAP</I> gene was expressed abundantly in skeletal muscle. The study suggested that <I>TCAP</I> gene might be a prospective candidate gene affecting muscle mass and meat quality traits in the pig and would lay the groundwork for the further investigations on the regulation and physiological function of porcine <I>TCAP</I> gene.
ER  -