TY  - JOUR
T1  - Expression of Deiodinase Gene <I>mRNA</I> after Melatonin Manipulated in Cashmere Goats Skin During Cashmere Growth
AU - Jia, Zhihai AU - Zhu, Xiaoping AU - Liu, Haiying AU - Zhang, Wei AU - Sun, Maohong AU - Kong, Xianghao AU - Yue, Chunwang 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 11
SP  - 1837
EP  - 1842
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.1837.1842
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.1837.1842
KW  - Monodeiodinase
KW  -gene mRNA expression
KW  -real-time RT-PCR
KW  -melatonin
KW  -cashmere fibre
KW  -cashmere goats
AB  - The aim of this research was to investigate the changes of the Monodeiodinase (MD) gene <I>mRNA</I> in skin of cashmere goats from the initiation of cashmere fibre growth to normal growth. The Melatonin (MT) implants were used in order to initiate growth of cashmere fibre before normal time. Real-time reverse transcription quantitative Polymerase Chain Reaction (real-time PCR) was used to determine the MD gene <I>mRNA</I> expression levels of skin. The results show that the MT concentration was significant differences after administration from July to November the cashmere fibre growth rate was markedly greater in group of MT implant (M group) than that of the group of control (C group) in July (p&lt;0.01), August (p&lt;0.001) and September (p&lt;0.05), the expression of cashmere goat skin MDII mRNA is gradually increased from June to September and then decreased gradually after the implant MT MDII mRNA expression increased rapidly, M and C group in July was significantly different (p&lt;0.01) and August are still significant differences (p&lt;0.05), the M and C group MDIII mRNA expression showed a downward trend from June to November in Cashmere goat skin and the M and C group did not appear significant differences (p&gt;0.05) in the monthly. These results suggest that the expression levels of MDII mRNA may be involved in the process of cashmere growth, it expression may have a specific signaling pathway in cashmere goats skin, especially in the initiation of cashmere fibre growth period.
ER  -