TY  - JOUR
T1  - Association of Single Nucleotide Polymorphism in Pancreatic Lipase Gene with Growth-Related Traits in Japanese Black Beef Cattle
AU - , Takahisa Yamada AU - Tanomura, Hideki AU - , Youji Muramatsu AU - , Takuji Yamamoto AU - , Takeshi Ohta AU - , Hiroyuki Kose 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 9
SP  - 1346
EP  - 1349
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.1346.1349
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.1346.1349
KW  - Association
KW  -beef cattle
KW  -growth-related trait
KW  -Japanese Black breed
KW  -single nucleotide polymorphism
KW  -PNLIP
AB  - Growth performance as well as marbling is the main breeding objectives in Japanese Black cattle, the major beef breed in Japan. Researchers have recently reported that a Single Nucleotide Polymorphism (SNP) referred to as rs41648172 in intron 6 region of the Pancreatic Lipase (<I>PNLIP</I>) gene was associated with marbling in Japanese Black beef cattle with the T allele being associated with a high level of marbling. The PNLIP is known to be involved in the hydrolysis of dietary triglycerides to fatty acids which is essential for the intestinal absorption of long-chain triglyceride fatty acids. Thus, the PNLIP was considered as a functional candidate for the gene responsible for growth performance. In this study, researchers analyzed the effect of the PNLIP rs41648172 SNP genotypes on the growth-related traits in Japanese Black beef cattle. The SNP was associated with carcass weight, rib eye area, rib thickness and daily gain in the experiment using 367 paternal half-sib progeny steers from a sire homozygous for C allele at the rs41648172 in Japanese Black beef cattle. The SNP was also associated with carcass weight, rib eye area and daily gain in the experiment using 587 paternal half-sib progeny steers from a sire homozygous for T allele at the rs41648172 in Japanese Black beef cattle. These findings suggest possible effect of the rs41648172 on the growth-related traits in Japanese Black beef cattle. The PNLIP SNP polymorphism may be useful for effective marker-assisted selection to increase the beef productivity in Japanese Black beef cattle.
ER  -