TY  - JOUR
T1  - Endothelin-1 Detection in Bronchial Biopsy of Horses
AU - Fulvio, Laus AU - Emanuele, Paggi AU - Francesca, Mariotti AU - Matteo, Cerquetella AU - Beniamino, Tesei 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 7
SP  - 1063
EP  - 1066
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.1063.1066
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.1063.1066
KW  - Horse
KW  -respiratory disease
KW  -endothelin
KW  -biopsy
KW  -immunohistochemical analysis
KW  -proinflammatory
AB  - Endothelin-1 (ET-1) is the most potent vasoconstrictor molecule up to now identified. Endothelial cells, smooth muscle cells and epithelial cells of airways are able to produce this potent proinflammatory, secretagogues and bronchoconstrictors mediator also implicated in the pathogenesis of inflammatory diseases of airways in human being. Some studies demonstrated the presence of endothelin-1 in respiratory apparatus of the horse and also that ET-1 cause bronchial contraction on bronchial rings of horses <I>in vitro</I>, especially in horse with respiratory disease.
ER  -