TY  - JOUR
T1  - Discover of a Novel SNP Highly Associated with Chicken Blue Egg
AU - Wang, A.R. AU - Li, J.Y. AU - Deng, X.M. AU - Wang, X.T. AU - Wang, Z.P. AU - Liu, R.F. 
JO  - Journal of Animal and Veterinary Advances
VL  - 10
IS  - 1
SP  - 92
EP  - 95
PY  - 2011
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2011.92.95
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2011.92.95
KW  - Chicken
KW  -association
KW  -linkage
KW  -chromosome
KW  -blue egg
KW  -SNP
AB  - Blue egg is caused by a dominant mutation, Oocyan (O) which is previous located on short arm of chicken chromosome 1 but precise genetic mechanism underlying blue egg is still unknown so far. In this study, we found a SNP (g.67419892-67419904del13) significantly associated with blue egg using 126 browned-shelled chickens and 202 blue-shelled chickens. The allelic and genotypic frequencies of g.67419892-67419904del13 are significantly higher in blue-shelled chickens (92.5 and 87.1%) compared with brown-shelled chickens (10.7 and 8.7%, p&lt;0.0001). Moreover, the genetic distance between O and g.67419892-67419904del13 is estimated to be over 2 cM (LOD = 13.51) using 149 F<SUB>2</SUB> offspring from mating between blue-shelled males and brown-shelled females. Apparently, the marker is useful for the cloning of O and marker aid selection of blue-shelled chicken breed.
ER  - 