TY  - JOUR
T1  - Analysis on the Genetic Variation of <I>KAP3.1</I> and <I>KAP6.1</I> Gene in 6 Rabbit Populations
AU - Tian-Wen, Wu AU - , Li-Ting AU - , Feng-Kai AU - , Mao-Liu-Liu AU - Bi-Chun, Li AU - Xin-Sheng, Wu 
JO  - Journal of Animal and Veterinary Advances
VL  - 10
IS  - 7
SP  - 894
EP  - 899
PY  - 2011
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2011.894.899
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2011.894.899
KW  - Rabbit
KW  -KAP3.1 gene
KW  -KAP6.1 gene
KW  -genetic variation
KW  -Hardy-Weinberg equilibrium
KW  -China
AB  - Researchers had scanned the complete CDS of rabbit <I>KAP3.1</I> and <I>KAP6.1</I> gene for the 1st time by PCR-SSCP and detected that their homology with mouse, chimpanzee, human, sheep and goat were &gt;80%, suggesting that the two genes among different species kept high conservation in evolution. In this study, three genotypes and two alleles were found at KAP3.1-1 locus having one silent mutation (C91T) and there were two alleles and three genotypes in 5 un-translated region of<I> KAP6.1</I> gene with the A 755 G mutation of the enhancer region. Herein, the distribution of these genotypes in all populations was consistent with the Hardy-Weinberg equilibrium and showed intermediate or low diversity. The result suggested a theoretical reference to the breeding of rabbit wool quality whether <I>KAP3.1</I> and<I> KAP6.1</I> gene could be a molecular marker or not.
ER  -