TY  - JOUR
T1  - Association of <I>MyF5, MyF6 </I>and <I>MyOG</I> Gene Polymorphisms with Carcass Traits in Chinese Meat Type Quality Chicken Populations
AU - Wang, Yan AU - Zhao, Xiaoling AU - Lan, Xi AU - Zhang, Zhichao AU - Yin, Huadong AU - Zhu, Qing 
JO  - Journal of Animal and Veterinary Advances
VL  - 10
IS  - 6
SP  - 704
EP  - 708
PY  - 2011
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2011.704.708
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2011.704.708
KW  - polymorphism
KW  -meat quality
KW  -Myf5/Myf6/MyoG genes
KW  -carcass traits
KW  -Chicken
KW  -genotypes
AB  - The <I>MyoD</I> gene family has been proposed to profoundly modulate muscle development and carcass performance in farm animals. In this study, researchers examined Single Nucleotide Polymorphisms (SNPs) in the exons of the <I>Myf5</I>, <I>Myf6</I> and <I>MyoG</I> genes using Polymerase Chain Reaction (PCR)-Single Strand Conformation Polymorphisms (SSCP) and DNA sequencing methods in 360 individuals from 6 commercial pure lines of Sichuan Daheng meat type quality chickens. About 2 SNPs (87T&gt;C and 96C&gt;T) in exon 1 of Myf5, 1 SNP (154T&gt;C) in exon 1 of MyoG and no variation in Myf6 were detected. The 96C&gt;T SNP in Myf5 was a rare variant and was not analyzed further. The association analysis of genotypes with carcass traits revealed that the genotypes of SNP (87T&gt;C) in Myf5 were significantly associated with Live Weight (LW), Carcass Weight (CW), Semi-Eviscerated Weight (SEW) and Eviscerated Weight (EW) (p&lt;0.05). The SNP genotypes (154T&gt;C) in MyoG were significantly associated with Live Weight (LW), Carcass Weight (CW), Eviscerated Weight (EW) and Breast Muscle Weight (BMW) (p&lt;0.05). The results suggested that <I>Myf5</I> and <I>MyoG</I> genes are potential major genes or are in close linkage disequilibrium with the QTL affecting carcass traits in this population of chickens. The 2 SNPs may potentially have use as markers for Marker-Assisted Selection (MAS) in chicken breeding.
ER  -