TY  - JOUR
T1  - Mesenchymal Stem Cells, Osteogenic Lineage and Bone Tissue Engineering: A Review
AU - Ibrahim, Rashid AU - Zuki Abu Bakar, Md. AU - Azmi Ibrahim, Tengku AU - Kaveh, Kamran 
JO  - Journal of Animal and Veterinary Advances
VL  - 10
IS  - 17
SP  - 2317
EP  - 2330
PY  - 2011
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2011.2317.2330
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2011.2317.2330
KW  - osteoblasts
KW  -bone tissue engineering
KW  -regenerative medicine
KW  -Malaysia
KW  -scaffold
KW  -Mesenchymal stem cell
AB  - Mesenchymal Stem Cells (MSC) are multipotent non-hematopoietic progenitor cells with an extensive proliferation potential and ability to differentiate into various cell types including osteoblasts, chondroblasts, myocytes, adipocytes and neurocytes. MSC is a cell of bone marrow population that plays a key role in bone marrow homeostasis and regulates the maturation of both hematopoietic and non-hematopoietic cells. Mesenchymal stem cells have been emerged in promising therapeutic modality for tissue regeneration and repair. Treatment of graft versus host disease, heart regeneration following infarction, cartilage and bone repair and treatment of osteogenesis imperfecta are only few therapeutic application of MSC. Tissue engineering in recent years opened a new frontier to replace the affected tissue by MSC assistance. Mesenchymal stem cell seems to be the future powerful tool in therapeutic application of regenerative medicine in repairing and replacing the impaired organs. The main aim of current review is to have a more precise look to MSC, its proliferation and differentiation potentials, therapeutic application and bone tissue engineering.
ER  -