TY  - JOUR
T1  - Effects of Chinese Herbal Medicine Additives on Antioxidant Status, Serum Biochemical Parameters and Digestive Enzymatic Activities in Weaned Piglets
AU - Yin, Z.J. AU - Huang, L. AU - Zhang, C.H. AU - Ding, Y.Y. AU - He, X.L. 
JO  - Journal of Animal and Veterinary Advances
VL  - 10
IS  - 15
SP  - 2004
EP  - 2009
PY  - 2011
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2011.2004.2009
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2011.2004.2009
KW  - digesive enzymatic activities
KW  -serum biochemical parameters
KW  -Chinese herbal medicine additive
KW  -China
KW  -antioxidant status
KW  -Weaned piglets
AB  - The study investigated the effects of Chinese Herbal Medicine Additives (CHMD) supplemented diets on weaned piglets antioxidant status, serum biochemical parameters, digesive enzymatic activities in a 3 weeks trial. Total of 144 crossbred (Duroc x Landrace x Yorkshire) weaning piglets (BW = 5.86&plusmn;0.24 kg) from 18 L with an age of 21 days were selected and divided randomly into 4 groups balanced for sex, weight and litter origin. In each group, the piglets were divided randomly into 3 pens (replicates, 12 pigs per pen), a corn-soybean meal-expanded soybean basal diet without antibiotics or probiotics was used as control and the other 3 groups were fed the control diet supplemented with the CHMD at rations of 0.5, 1 and 1.5% (wt/wt). After completion of the feeding experiment, 3 piglets from each treatment were randomly selected to determine the antioxidant status, serum biochemical parameters, digesive enzymatic activities. In the 3 weeks trial, the data showed that the 1% CHMD group had higher protease activity in stomach digesta than the control and 0.5% CHMD group (p&lt;0.01) than 1.5% CHMD group (p&lt;0.05). The 1.5% CHMD group showed similar significant difference in protease activities of piglets compared with the control group (p&lt;0.05). The 1% CHMD group had higher lipase activity than the control group in the stomach and jejunum digesta (p&lt;0.01) in the duodenum and ileum digesta (p&lt;0.05) and than the 0.5% CHMD group in the stomach and jejunum digesta (p&lt;0.05). The 1% CHMD group had higher amylase activity than the control group in the jejunum digesta (p&lt;0.01) in the duodenum and ileum digesta (p&lt;0.05) and than the 0.5% CHMD group and 1.5% CHMD group in the jejunum digesta (p&lt;0.05). The 1.5% CHMD group had higher amylase activity than the control group in the ileum digesta (p&lt;0.05). The 1% CHMD group had higher T-AOC and CAT activities than the control group and 0.5% CHMD group (p&lt;0.01), than the 1.5% CHMD group (p&lt;0.05). The 1.5% CHMD group had higher T-AOC and CAT activities than the control group (p&lt;0.05). The 1% CHMD group had higher GSH-PX and SOD activities than the control group (p&lt;0.05). The 1% CHMD group (p&lt;0.01) and the 1.5% CHMD group (p&lt;0.05) had lower MDA content than the control group. Compared with the control group, dietary supplementation of 1% CHMD reduced the serum BUN (p&lt;0.05) and increased the total serum protein (p&lt;0.05), reduced the serum triglyceride and total cholesterol contents (p&lt;0.01). The results show that the CHMD used in this study as a dietary additive could enhance the antioxidant status, serum biochemical parameters, digesive enzymatic activities in weaned piglets, additionaly imply that the dose of 1% CHMD supplement is the most ideal concentration to achieve the most beneficial effects.
ER  -