TY  - JOUR
T1  - Histopathological Effects of Mid-Urethral Tapes: An Animal Study on Female Rats
AU - Mesgari, Mehran AU - Roshanghar, Leila AU - Zeynali, Mehdi AU - Mohajery, Darioush AU - Hajebrahimi, Sakineh 
JO  - Journal of Animal and Veterinary Advances
VL  - 10
IS  - 15
SP  - 1968
EP  - 1973
PY  - 2011
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2011.1968.1973
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2011.1968.1973
KW  - stability
KW  -Wistar rats
KW  -Midurethral tapes
KW  -incontinence therapy
KW  -compatibility
AB  - The midurethral tapes available in market to be used for incontinence therapy need further to be studied on animal models using both photomicroscope and electron microscopy facilities. The aim of this study was to assess biomechanical and histopathologic effects of TOT, TVT and IVS and Mersilene tapes implanted in rat tissue. Thirty female Wistar rats, aged 10 weeks with an average weight of 220 g were randomly allocated into five groups (A-E) of 6 animals each. Groups A-E were assigned to receive one of the four brands of tapes designed to be used in anti-incontinence surgery and the last group received a sham surgery as control. After 6 and 12 weeks, they were assessed biomechanically and histologically using both photo microscopy and electron microscopy techniques. The rat tissue reacted differently to the types of midurethral tapes. Overall, regarding tissue compatibility, TOT and IVS are slightly better than TVT. Mersilene as a positive control showed lower compatibility and stability. TOT had base stability higher than other types.
ER  -