TY  - JOUR
T1  - Growth of <I>Staphylococcus aureus</I>, <I>Candida albicans</I>, <I>Escherichia coli</I> and <I>Pseudomonas aeruginosa</I> in Propofol, Thiopental and a 1:1 Propofol-Thiopental Mixture
AU - Gul, Nihal Y. AU - Gedikoglu, Suna AU - Ozakin, Cuneyt AU - Bilgin, Hulya AU - Topal, Ayse 
JO  - Journal of Animal and Veterinary Advances
VL  - 9
IS  - 10
SP  - 1432
EP  - 1435
PY  - 2010
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2010.1432.1435
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2010.1432.1435
KW  - thiopental
KW  - mixture
KW  -propofol
KW  -Intravenous anesthetics
KW  -bacteria
KW  -growth rate
AB  - Extrinsic contamination of propofol is thought to be a source of postoperative sepsis. Researchers studied growth of <I>Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli</I> and <I>Candida albicans</I> in propofol, thiopental and in a 1:1 propofol-thiopental mixture. All microorganisms were taken from standard stock cultures. Half of the samples were incubated at 20&deg;C and the rest were stored at 4&deg;C for 120 h. Growth of microorganisms in each solution was compared by counting the number of the Colony-Forming Units (CFUs) at 0, 3, 6, 24, 72 and 120 h. Propofol supported the growth of all four microorganims at both temperatures. In contrast, thiopental and the 1:1 propofol-thiopental mixture exhibited markedly bactericidal properties on <I>E. coli, C. albicans</I> and<I> P. aeruginosa </I>and bacteriostatic effect on <I>S. aureus</I>.
ER  -