TY  - JOUR
T1  - Protective Effects of Nano-ZnO on the Primary Culture Mice Intestinal Epithelial Cells in <I>in vitro</I> Against Oxidative Injury
AU - Zhisheng, Wang AU - Dawei, Ai AU - Anguo, Zhou 
JO  - Journal of Animal and Veterinary Advances
VL  - 8
IS  - 10
SP  - 1964
EP  - 1967
PY  - 2009
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2009.1964.1967
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2009.1964.1967
KW  - Intestinal epithelium cell
KW  -nano-ZnO
KW  -antioxidant
KW  -antioxidant enzymes
KW  -integrity
KW  -in vitro
AB  - Nano-ZnO is a new products, which may used to be feed resources. The aim of this study was to exam, whether nano-ZnO is able to protect cell integrity from potential damage by free-radical oxidative injury. A 3x3 factorial experiment was used to investigate the interaction between particle diameter (15, 50 and 100 nm) and concentration (0.4, 1.6 and 6.4 μg mL<SUP>-1</SUP>) of the primary culture mice Intestinal Epithelium Cell (IEC) in <I>in vitro</I>. The results indicated that the all the nano-ZnO groups MTT OD value were significantly higher than the perhydrol group (p<0.05) and LDH decreased, but not significant (p>0.05). The MDA content in all the nano-ZnO groups were decreased significant (p<0.01). The SOD and CAT in all nano-ZnO groups were higher than the perhydrol group (p>0.05). The results shown that nano-ZnO released the IEC oxidative injury.
ER  -