TY  - JOUR
T1  - Cytokine Immune Response in Mexican Creole and Commercial Pigs Under Uncontrolled Conditions
AU - , K. Mejia-Martinez AU - , C. Lemus-Flores AU - , J.F. Zambrano-Zaragoza AU - , R. Ramirez-Necoechea AU - , D. Mota-Rojas AU - , M. Alonso-Spilsbury 
JO  - Journal of Animal and Veterinary Advances
VL  - 7
IS  - 5
SP  - 625
EP  - 629
PY  - 2008
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2008.625.629
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2008.625.629
KW  - Cytokines
KW  -humoral immune response
KW  -creole pigs
AB  - The aim of the study was to measure the cytokine immune response in 2 Mexican creole biotypes and compare it to commercial pigs (COM) as disease resistance indicators. Twenty six commercial (COM), 25 Cuino (CP) and 25 Mexican hairless (MHP) pigs were vaccinated with a commercial bacterin containing <I>Salmonella</I>, <I>E. coli</I> and <I>Pasteurella</I> at 45 days of age; a sample was taken a week later to test serum levels of interleukin 1  (IL-1 ), interleukin 4 (IL-4), interferon-gamma (INF- ) and alfa tumor necrosis factor (TNF- ). Cytokine quantification serum tests were carried out with commercial kits using the ELISA sandwich method. The Kruskal-Wallis test was used to compare cytokine concentrations and the Wilcoxon test was run to look for differences among breeds. IL-1  and IL-4 production was higher in HMS as compared to the other breeds. No significant differences between INF-  and TNF-  production were seen. Results suggest that MHP have a higher response capacity before an infection, compared to the other breeds.
ER  -