TY  - JOUR
T1  - Short-Term Diabetes has no Influence on Mast Cell Infiltration and Reactivity During the Local Shwartzman Reaction
AU - , A.C. Rodriguez-Aguirre AU - , C.F. Rodriguez-Ortega AU - , A.M. AU - , Nevarez-Garza AU - , L.E. Rodriguez-Tovar AU - , G. Hernandez-Vidal AU - , R. Ramirez-Romero 
JO  - Journal of Animal and Veterinary Advances
VL  - 7
IS  - 3
SP  - 258
EP  - 262
PY  - 2008
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2008.258.262
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2008.258.262
KW  - Local shwartzman reaction
KW  -mast cells
KW  -short term diabetes
KW  -lipopolysaccharide
AB  - Mast cells numbers and reactivity status based on degranulation was determined in the skin of diabetic rabbits subjected to a local Shwartzman reaction. Diabetes was induced by a single intravenous injection of alloxan. The local Shwartzman reaction was induced seven days after by two inoculations of <I>Salmonella typhimurium</I> lipopolysaccharide. Preparatory injection was received in the skin and 24 h later; the provocative injection was administered intravenously. Rabbits were killed at the next day. Skin samples were fixed in Carnoy&#8217;s and mast cell were identified employing a low pH toluidine blue stain. Results showed that Shwartzman reaction influences dramatically the increment and reactivity of mast cells independently from diabetes. In this model of acute inflammatory response diabetes has no influence on mast cells.
ER  -